Episode 1
A priest is genitally mutilated during a mugging; a patient dies after a routine liposuction; Jeffrey refuses to perform surgery on a child.
Episode 2
A heart becomes available for transplant, but there are two patients waiting and Drs. Geiger and Watters must choose which patient will receive the heart. Jeffrey tries to place Alicia into an exclusive kindergarten. Aaron tries to hold a welcoming party for the new doctors.
Episode 3
A doctor with Tourette's Syndrome is brought to Chicago Hope to operate on an infant with a severe heart defect. A patient comes into the ER with, what he claims to be, Albert Einstein's brain and gives it to Dr. Wilkes. A woman is using plastic surgery to make herself look like a Barbie Doll.
Episode 4
Dr. McNeil goes to magnificent lengths to save the arm of a young baseball star. A little girl is brought into the ER after being hit by a car.
Episode 5
The doctors fight to save Cacaci's life after he jumps from a six story building in a suicide attempt, although Cacaci's fiancee says that someone pushed him off the building.
Episode 6
A widow wants to be impregnated with the sperm of her former husband. Rats take over the hospital.
Episode 7
The hospital is quarantined after a deadly virus is discovered; a child is missing in the hospital.
Episode 8
Dr. Alberghetti performs a surgery with another surgeon, who is in Sri Lanka.
Episode 9
On the way to a football game, Aaron and Jack get sidetracked... after they find themselves in a hostage situation with 3 wounded patients, a loose gunman, and the police about ready to enter the building.
Episode 10
Dr. Hanlon must fight against her department heads when they decide they no longer want her to perform pro-bono operations. Dr. Alberghetti tries to help a young man with a staph infection.
Episode 11
Gina operates on a surgeon who's been diagnosed with Parkinson's disease.
Episode 12
A hepatitis scare forces Dr. Geiger to call for outside help; Dr. Simon's misdiagnosis causes her to doubt herself.
Episode 13
A teenager is forced to live his life as a girl after the slip of a knife, and McNeil goes to court to try to help.
Episode 14
A father is told he can only donate his liver to one of his children, after both go into liver failure. Rose Webber comes back to Chicago Hope and finds that Aaron has started a new relationship -- with Gina.
Episode 15
Keith discovers a heart murmer while giving Alicia a physical. Jeremy performs an appendectomy on Siamese twins.
Episode 16
A mentally challenged couple enters the hospital. The husband needs open heart surgery. The wife discovers that she can't become pregnant after she was sterilized without her consent.
Episode 17
Shutt and Simon invent a procedure and use it to save the life of a girl. McNeil treat a wrestler who's been using steroids.
Episode 18
McNeil's friend is shot. Pancreatic cancer effects one of the conjoined twins that have entered the hospital.
Episode 19
The hospital is purchased by an HMO, and immediately suffers budget cuts. During an operation that Miller is filming for a documentary, the heart stops beating on both the patient and her unborn child.
Episode 20
McNeil goes against procedure and red tape and performs a hip replacement surgery. Shutt and Simon transplant a computer into a patients brain. Alberghetti tries to ignore her feelings for Miller.
Episode 21
Shutt's patient wakes up after being in a coma after 15 years. A man is denied health coverage, after saving Miller's life.
Episode 22
Rumors fly that the hospital is about to be sold again; a man seriously injured in an accident wants to be the guinea pig for the computer program he's invented that can help him move again.