Episode 1
Potential contestants hit the runway and compete to see who can take the best selfie; Miss J returns to the judging panel.
Episode 2
Semifinalists model various seasons in a limited amount of time during a rigorous subway challenge; a nighttime photo shoot at the beach gets steamy.
Episode 3
Tempers flare and relationships ignite as the 14 contestants move into their new home; the models compete in a runway challenge wearing only silly string; behind-the-scenes look on the rain-themed intro.
Episode 4
With a love triangle brewing in the house, not all models bring their A-game to an optical illusion photo shoot. The eagerly awaited make-over day arrives, and one model to unveils a never-before-seen look while another suffers a breakdown.
Episode 5
Tyra helps the models prepare for a sexy photo shoot; unexpected chemistry sparks between two models before a challenge involving stilts; a model breaks a house rule after a night of partying.
Episode 6
The models are tasked with mastering the ultimate hair whip for a wind-blown photo shoot. One girl is given a penalty and is allowed only five frames to capture the perfect image. Later, Nick Cannon gives the models a chance to be the face of his new ad campaign.
Episode 7
The contestants audition for a walk-on role on a TV show; hurtful comments lead to an icy photo shoot.
Episode 8
A photo shoot challenge leads two models to realize they need to put their personal relationship aside; the models discover common ancestry links during a futuristic sci-fi photo shoot.
Episode 9
After a private runway session with Miss J, the models must book fashion shows with designers including Betsey Johnson; models are paired up during a photo shoot for a hair product.
Episode 10
An eliminated model returns to the competition; the models must keep their composure during a challenge at a former slaughterhouse with a dark history; a fashion shoot with a focus on HIV and AIDS awareness.
Episode 11
A recap of the competition so far.
Episode 12
The models travel to Seoul, Korea, where they take part in a group dance shoot judged by BtoB; a bad habit limits one model's potential for success.
Episode 13
During a timed challenge, the models race to locations in Seoul; a models winds up isolated after getting caught in a lie; a confrontation occurs between a model and Yu Tsai.
Episode 14
The five remaining models perform a bilingual scene with Korean soap opera actors before tackling a night-time photo shoot that has them dressing up to recreate iconic images of the King and Queen of American pop culture: Elvis Presley and Marilyn Monroe. But history comes back to haunt the models when each is asked to confront demons from their past.
Episode 15
The final four models are shown by Tyra her new cosmetics line and they are challenged to make a commercial shoot with the help of some of the previously eliminated girls.
Episode 16
Cycle 21 concludes with the remaining three models participating in a final runway fashion show in Seoul for designer Lie Sang Bong. Later, Tyra reveals the winner. Kpop band 2NE1 perform.