Episode 1
Susan and Mary purposely turn themselves into babies while the parents are out, and Johnny has to keep them safe from the irresponsible babysitter Gil; this interferes with a party he and Dukey had been planning.
Episode 2
Johnny tricks his sisters into letting him have teleporting powers. Susan and Mary mess with the powers to get revenge. Later the twins accidentally get them caught in a middle of an art robbery.
Episode 3
After Johnny lands his bike into a garbage truck, he becomes a Lady Bird Scout and tries to sell 1,000 boxes of cookies to get a new one. Little does he know, Sissy wants the bike as well, but for a better reason.
Episode 4
Johnny goes back in time in order to get a sloth bone for the twins, but when he returns he becomes a caveman, interfering with his grounding from selling Hugh's personal items.
Episode 5
Johnny and Dukey run away when Johnny's parents say he's old enough to do chores but not old enough to watch PG-13 movies.
Episode 6
Johnny steals a portable black hole, which later creates an early apocalypse.
Episode 7
Johnny joins forces with Dark Vegan to get him back to his home planet.
Episode 8
Susan and Mary build Johnny a robot in order to help him do his homework, but the robot ends up stealing things for Johnny.
Episode 9
Susan and Mary switch Johnny and Hugh's brains after the two make a bet that involves taking on each other's lives.
Episode 10
Johnny and Dukey try to get in a dog show which only allows perfectly groomed and trained dogs.
Episode 11
Dukey drinks a liquid which makes him turn into a monster. To make matters worse, a dog catcher (and later Mr. Black and Mr. White) are after him.
Episode 12
Johnny wants to get a trophy to put in his trophy case. Susan and Mary get obsessed with winning, so the three of them enter The Pork Belly River Jumpoff to win 1 million dollars and a trophy.
Episode 13
Susan and Mary make fortune cookies that come true, and Johnny sells them with the typical drastic results.
Episode 14
The twins' latest invention accidentally makes them dumb thanks to Johnny right before their scholarship interview.
Episode 15
Johnny gets hired to stop Bling-bling from kissing Susan, but Johnny turns on the sisters once Bling-Bling bribes him.
Episode 16
Johnny turns into a mouse for Susan and Mary, but when Mr. Mittens comes, things get chaotic. This episode is a parody of Tom and Jerry.
Episode 17
Johnny tries to get invited to a party to stop a villain. NOTE: Susan and Mary don't appear in this episode.
Episode 18
Mr. Whacko invents a new helium gum that lifts kids into the sky, and Johnny must save them.
Episode 19
Johnny travels to 1845 when school was easier, but he gets stuck there because the power supplier to the Turbo Time Tea house hasn't been invented yet. The sisters and Johnny try to find outdated technology to power the tea house.
Episode 20
Johnny creates a magnetic force field on the Earth which makes Porkbelly the new north pole.
Episode 21
Johnny and Dukey get framed for stuff that Johnny and Dukey look alike robots (which Mr. Black and Mr. White made) do around Porkbelly.
Episode 22
Johnny keeps attempting to ride down Suicide hill, but Susan and Mary keep redeeming Johnny's coupons.
Episode 23
Johnny gets X-Ray goggles.
Episode 24
Johnny and Dukey decide to remain in super hero mode permanently but find being a superhero is harder than they think.
Episode 25
The twins upgrade Johnny's new cell phone. Later the phone becomes too intelligent and begins hacking government space missiles.
Episode 26
Johnny goes on a trip to the museum and brings the things to life, including a mummy.
Episode 27
Johnny's mail order foam monster becomes a real monster once the twins swap the water with their bottle of "side effects".
Episode 28
When Sissy considers Johnny too gross to help her in a science project, he begs Susan and Mary to change his personality.
Episode 29
Johnny poses as a princess in order to prevent a war. Meanwhile, Susan and Mary decide that they would like to act like normal girls.
Episode 30
After getting his 99th detention, Johnny learns he must perform 99 good deeds or he will be sent to military school.
Episode 31
Johnny and Dukey challenge his sisters, their friends, and their enemies to a survival challenge in which the winning team gets hundreds of dollars in gift certificates.
Episode 32
While the tests go on vacation, Johnny and Dukey try to get back into their hotel room and avoid the hotel manager that doesn't allow pets.
Episode 33
Mr. Black moves in with the Tests after he embarrasses Mr. White at the dance contest auditions.
Episode 34
Johnny's parents keep setting Johnny up with new friends. When those don't work out, Johnny reveals Dukey's intelligence. Later, Dukey spends more time helping Johnny's parents instead of playing with Johnny.
Episode 35
Johnny once again has to protect Susan from Bling Bling Boy who is determined to have her as his valentine.
Episode 36
Susan and Mary both want Gil to go on a date with them, so they put up a wrestling match using rough guts (Susan uses Johnny's while Mary uses a lion's), but it leads to destructive results.
Episode 37
Johnny goes to the beach to surf, but there are no waves, so Susan and Mary build a wave making machine and special surfboard for him.
Episode 38
Johnny and Dukey try to help Brain Freezer get a girlfriend.
Episode 39
Johnny becomes obsessed with domination after Susan and Mary bring his chess pieces to life.
Episode 40
Johnny uses one of his sisters' inventions to bring two cartoon characters to the real world in order to scare Sissy out of the house, but the characters mistake Porkbelly for a zombie world and try to destroy it.
Episode 41
It's Lila's birthday and the family spends the morning to make her birthday a success. Johnny struggles to make her breakfast, Hugh tries to figure out a good but inexpensive gift for her, and the twins keep trap Lila in her bedroom until Hugh and Johnny are ready.
Episode 42
Johnny wants to become a internet sensation.
Episode 43
Johnny is dragged into Susan and Mary's plan to get Gil to be in a sleep-over, but Bling-Bling Boy and Dark Vegan's daughter Jillian become involved as well, with the usual chaos ensuing.
Episode 44
Johnny gets a wart, and when his sisters try to get rid of it, it gives the wart intelligence and seems to make Johnny's life better, but he tries to take over his body as he gets more powerful.
Episode 45
When Susan and Mary turns Johnny into a fish as part of one of their experiments, Hugh flushes him down the toilet by mistake where he ends up in the sewer, and he has to swim for his life when he runs into an alligator.
Episode 46
Johnny ditches school with a relentless truant officer in hot pursuit.
Episode 47
Dark Vegan once again tries to destroy Johnny, who is trying to cheer up lonely Repto-Slicer.
Episode 48
Hugh wants to train Johnny to be good at sports so that he could get a sports scholarship to college.
Episode 49
Johnny, his friends, and his enemies all compete in a boat race against an arrogant rowing team.
Episode 50
Johnny is determined to get a flytrap plant from his sisters for his school's science fair.
Episode 51
Johnny is in charge of the school play about recycling while Susan and Mary create a garbage-eating monster.
Episode 52
The general takes away the lab, and than builds agent cyborgs. They charge up Johnny X and their friends to stop them!
