Episode 1
Jimmy welcomes former professional basketball player Charles Barkley plus an interview with and musical performance by The Chicks.
Episode 2
Episode 3
Actor Riz Ahmed ("Mogul Mowgli" and "The Long Goodbye"); Tim McGraw (album, "Here on Earth") talks and performs.
Episode 12
Actor Armie Hammer (Rebecca (2020)); actor Marlon Wayans (On the Rocks (2020)); Jaden Smith performs;
Episode 19
Episode 22
Episode 25
Episode 26
Episode 27
TV host David Letterman ("My Next Guest Needs No Introduction with David Letterman"); actress Gillian Jacobs ("Come Play"); Gracie Abrams performs.
Episode 43
Actress Natalie Portman (book, "Natalie Portman's Fables"); "Who Wants to Be a Millionaire" celebrity winner Russell Dickerson performs;
Episode 45
Episode 46
Episode 58
Tessa Thompson and Paul Bettany guest. Steve Earle performs.
Episode 65
Episode 89
Episode 97
Jamie Foxx; Lauren Graham; AJR performs
Episode 98
Octavia Spencer, Melissa McCarthy, Nasim Pedrad, Fitz, Bryce Vine
Episode 99
David Alan Grier, Topher Grace, All Time Low
Episode 100
Ray Romano, Romany Malco, Nessa Barrett, Jxdn, Travis Barker
Episode 101
Luke Bryan, Katey Sagal
Episode 102
Mark Wahlberg, Hunter Biden, The Wallflowers
Episode 103
Andy Garcia, Clayton Kershaw, Noga Erez
Episode 104
John Stamos, Katheryn Winnick, Easy Life
Episode 105
Terry Crews, Corinne Foxx, Greta Van Fleet
Episode 106
Anderson Cooper, Emily VanCamp, Zoe Wess
Episode 107
Riz Ahmed, Andra Day
Episode 108
Ellen DeGeneres, Billie Joe Armstrong, Jimmie Allen, Brad Paisley
Episode 109
George W. Bush, Maroon 5
Episode 110
Gal Gadot, Eric Andre, Kale
Episode 111
Arnold Schwarzenegger; Kyla-Drew.
Episode 112
Dave Grohl performs; actor Billy Porter.
Episode 113
Justin Theroux; Mike Lindell; Tom Jones.
Episode 114
Maya Rudolph; Malcolm Gladwell.
Episode 115
Sean Hayes; Casey Wilson; Jason Aldean.
Episode 116
Rosario Dawson, Anthony Fauci, and Anitta.
Episode 117
Rob McElhenney; Uzo Aduba; Middle Kids.
Episode 118
Julianna Margulies; Daniel Dae Kim.T
Episode 119
Actor Ewan McGregor; comic George Wallace; Lucky Daye and Yebba perform
Episode 120
Model Heidi Klum; comic Mike Epps; Madness performs.
Episode 121
Wanda Sykes; Max Minghella; Mod Sun; Avril Lavigne
Episode 122
Chris Rock; Samira Wiley; Morray
Episode 123
Shaquille O'Neal, Patton Oswalt, Chase Rice
Episode 124
Gabrielle Union, Dwyane Wade, Kirby Howell-Baptiste, Royal Blood
Episode 125
Don Cheadle, Patti Harrison, Lake Street Dive
Episode 126
Ryan Seacrest, Yvonne Orji, Counting Crows
Episode 127
Elizabeth Banks, Danny Pudi, The Band CAMINO
Episode 128
Lena Waithe, Kelvin Harrison Jr., Allison Russell ft. Brittney Spencer & Brandi Carlile
Episode 129
Emily Blunt, Diego Boneta, The winner of “American Idol”
Episode 130
Emma Stone, Rory Scovel, Chloe Moriondo
Episode 131
Jimmy welcomes actor David Harbour, actor William Jackson Harper, and a musical performance by Half Alive.
Episode 132
Jimmy welcomes actress Rachel Weisz, actor Rob Riggle, and a musical performance by Willie Jones.
Episode 133
Jimmy welcomes comic Michael Che, actor Cillian Murphy, and a musical performance by The Linda Lindas.
Episode 134
Jimmy welcomes DJ Khaled, actress Florence Pugh, and a musical performance by Fousheé.
Episode 135
Jimmy welcomes actress Aidy Bryant, Katie Thurston (“The Bachelorette”), and a musical performance by John Mayer.
Episode 136
Jimmy welcomes actor Tom Hiddleston, actors Maya Erskine & Anna Konkle, and a musical performance by Chiiild.
Episode 137
Jimmy welcomes actor Liam Neeson, actress Gugu Mbatha-Raw, and a musical performance by T-Pain & Kehlani.
Episode 138
Jimmy welcomes authors Bill Clinton & James Patterson (“The President’s Daughter”), actor Wiz Khalifa, and a musical performance by Jackson Browne.
Episode 139
Jimmy welcomes actress Elisabeth Moss, actor Omar Sy, and a musical performance by Valerie June.
Episode 140
Jimmy welcomes actor Owen Wilson, actress Betty Gilpin, and a musical performance by Spice, Sean Paul & Shaggy.
Episode 141
Jimmy welcomes actress Zooey Deschanel, actor Sam Richardson, and a musical performance by Kodak Black.
Episode 142
Jimmy welcomes actor Dax Shepard, actress Monica Padman, actor Tony Hale, and a musical performance by Saweetie.
Episode 143
Jimmy welcomes actress Sarah Paulson, actor Frank Grillo, and a musical performance by Lucy Dacus.
Episode 144
Jimmy welcomes film director Quentin Tarantino, comic Iliza Shlesinger, and a musical performance by Lukas Nelson & Promise of the Real.
Episode 145
Jimmy welcomes actor Billy Crystal, actress Emma Corrin, and a musical performance by Seventeen.
Episode 146
Jimmy welcomes actor Chris Pratt, former attorney Michael Cohen, and a musical performance by The Isley Brothers & Snoop Dogg.
Episode 147
Guest host Wanda Sykes welcomes actor Ludacris, actress Kim Fields, and a musical performance by Merry Clayton.
Episode 148
Guest host Wanda Sykes welcomes actor Colin Farrell, comedian Quinta Brunson, and a musical performance by Japanese Breakfast.
Episode 149
Guest host Wanda Sykes welcomes actor Nick Kroll, basketball player Chiney Ogwumike, and a musical performance by Macy Gray & the California Jet Club.
Episode 150
Guest host Arsenio Hall welcomes actress Megan Fox, and a musical performance by Amorphous featuring Kelly Rowland.
Episode 151
Guest host Arsenio Hall welcomes professional basketball player LeBron James, actor Richard E. Grant, and a musical performance by Tainy x Yandel.
Episode 152
Guest host Phoebe Robinson welcomes comedian Chelsea Handler, professional basketball player Chris Bosh, and a musical performance by Moneybagg Yo.
Episode 153
Guest host Nick Kroll welcomes actor Seth Rogen, actor Winston Duke, and a musical performance by Gucci Mane & Big Walk Dog.
Episode 164
Guest host Anthony Anderson welcomes rapper Offset, actor Henry Golding, and a musical performance by Robin Thicke.
Episode 165
Guest host Anthony Anderson welcomes actors Margot Robbie, John Cena & James Gunn, and a musical performance by PnB Rock featuring Swae Lee & Pink Sweats.
Episode 166
Guest host Anthony Anderson welcomes actor Christian Slater, actor Chase Stokes, and a musical performance by Kem.
Episode 167
Guest host David Spade welcomes comic Whitney Cummings, skateboarder Jagger Eaton, and a musical performance by Sharon Van Etten & Angel Olsen.
Episode 168
Guest host David Spade welcomes actress Molly Shannon, actress Addison Rae, and a musical performance by Morgxn & Sara Bareilles.
Episode 169
Guest host Sarah Silverman welcomes actor James McAvoy, filmmaker Taika Waititi, and a musical performance by Max & Ali Gatie.
Episode 170
Guest host Sarah Silverman welcomes actor Kenan Thompson, actress Regina Hall, and a musical performance by The Killers.
Episode 171
Guest host Maren Morris welcomes singer-songwriter Willie Nelson, comic Megan Stalter, reality-TV personality Sutton Stracke, and a musical performance by Gabriels.
Episode 172
Guest host Julie Bowen welcomes actress Minnie Driver, actor Jacob Elordi, and a musical performance by Ashe.
Episode 173
Guest host Sean Hayes welcomes actress Awkwafina, actress Keke Palmer, and a musical performance by Daryl Hall & John Oates.
Episode 174
Guest host Sean Hayes welcomes actress Tracee Ellis Ross, actor Simu Liu, and a musical performance by Yola.
Episode 175
Guest host Stephen A. Smith welcomes rapper Snoop Dogg, Olympic sprinter Allyson Felix, and a musical performance by Nelly, Breland & Blanco Brown.
Episode 176
Guest host Niall Horan welcomes musician Lizzo, actor Cristo Fernandez, a musical performance by Kane Brown, and Jonas Brothers.
Episode 177
Guest host RuPaul welcomes comic Iliza Shlesinger, “RuPaul’s Drag Race” winner Symone, and a musical performance by Tai Verdes.
Episode 178
Guest host RuPaul welcomes actress Thandiwe Newton, actress Izzy G., and a musical performance by Belly.
Episode 179
Jimmy welcomes actress Tiffany Haddish, screenwriter David Chase, and a musical performance by Imagine Dragons.
Episode 180
Jimmy welcomes TV host Drew Barrymore, comic Sebastian Maniscalco, and a musical performance by Rufus Wainwright.
Episode 181
Jimmy welcomes former professional basketball player Shaquille O’Neal and a musical performance by Maisie Peters.
Episode 182
Jimmy welcomes actress Kristen Bell, actress Kirby Howell-Baptiste, plus an interview with and musical performance by Metallica.
Episode 183
Jimmy welcomes actress Jennifer Aniston, actor Dave Burd, and a musical performance by Bazzi.
Episode 184
Jimmy welcomes former professional basketball player Magic Johnson, actors Steve Lemme & Kevin Heffernan (“Tacoma FD”), and a musical performance by The Marias.
Episode 185
Jimmy welcomes TV host Bill Maher, actress Hannah Waddingham, and a musical performance by Carly Pearce.
Episode 186
Jimmy welcomes actor Curtis “50 Cent” Jackson and a musical performance by James Blake.