Episode 1
In 1977, after Billy Milligan is accused of multiple rapes near Ohio State University, experts question if he has multiple personality disorder.
Episode 2
Billy's troubled youth comes into focus via interviews with his siblings and childhood friends. At trial, his lawyers mount an unusual defense.
Episode 3
As Billy's celebrity rises, a new doctor disagrees with his diagnosis and alters his treatment. Later, Billy takes his care into his own hands.
Episode 4
With the help of friends and family, Billy goes on the run, changing his identity and mixing with some of Hollywood's biggest names.