Episode 1
A jailed Murdoch must prove his innocence amid police and government corruption after the constables are ambushed, Ogden is kidnapped, and Brackenreid goes missing.
Episode 2
Murdoch and Watts discover fraud after a wine connoisseur is poisoned.
Episode 3
A recording device made by Alexander Graham Bell assists in the investigation of a murder at a dinner honoring Helen Keller.
Episode 4
Murdoch investigates a surgeon performing cutting-edge organ transplants.
Episode 5
A spate of murders staged as suicides leads Murdoch to suspect a sequential killer targeting the elderly.
Episode 6
In an attempt to solve a murder, Crabtree and Constable Brackenreid go undercover at a boys school.
Episode 7
Murdoch investigates a car accident and uncovers sinister motives.
Episode 8
Brackenreid begins painting again and gets the attention of a wealthy patron while investigating an artist's murder.
Episode 9
After obituaries are published in advance of two men's deaths, Murdoch discovers more intended victims with a member of Station House Number Four among them. He must keep them alive before their predicted demise.
Episode 10
Murdoch investigates a death which may have been caused by a high-speed travel device.
Episode 11
Murdoch and Brackenreid find some unsportsmanlike behaviour while investigating the violent death of a cricket player on the pitch.
Episode 12
Murdoch investigates when a statue of the Virgin Mary gifted to his church begins miraculously weeping.
Episode 13
When the judge of a cooking contest is poisoned, Murdoch realizes that other competitors also tasted the tainted ingredient, including Crabtree and Margaret Brackenreid.
Episode 14
When Theodore Roosevelt sneaks into Canada for a hunting trip, Murdoch discovers the American President is the quarry.
Episode 15
As Murdoch investigates a murder with connections to vaudeville entertainers Harry and Al Jolson, Watts unravels a mystery about his own family.
Episode 16
Crabtree goes undercover at a chess tournament to investigate the murder of a Russian master.
Episode 17
Murdoch and Ogden put aside a personal matter when Nate Desmond is charged with murder.
Episode 18
Season Finale - An argument leads Murdoch to help a man looking for his missing wife, Crabtree contemplates his future with Nina and the Station House team works on a grisly murder.
